Venter’s scientific contribution was the creation of a synthetic cell. Craig Venter built a synthetic cell that genetic instructions created by humans entirely control.
The construction of a synthetic cell distinguished Venter’s scientific contribution. Craig Venter created a synthetic cell that is controlled by human-generated genetic instructions.
An artificial cell, synthetic cell, or minimum cell is a created particle that imitates one or more biological cell functions. Artificial cells frequently consist of biological or polymeric membranes encapsulating biologically active substances.
As a result, liposomes, polymersomes, nanoparticles, microcapsules, and a variety of other particles can be considered artificial cells.
As demonstrated in the different sections of this page, the terms “artificial cell” and “synthetic cell” are used in various fields and can have distinct meanings.
Some stricter definitions assume that the term “cell” refers directly to biological cells and that these structures must therefore be alive (or part of a living organism) and that the term “artificial” suggests that these structures are artificially constructed from the bottom up, i.e., from fundamental components.
Consequently, in synthetic biology, an artificial cell can be defined as a completely synthetic cell that can capture energy, maintain ion gradients, contain macromolecules, store information, and replicate. This type of synthetic cell has not yet been created.
In some instances, however, the term “artificial” does not always mean that the entire structure is artificial; rather, it might allude to the concept that certain functions or structures of biological cells can be altered, simplified, replaced, or augmented by a synthetic entity.
In various domains, the term “artificial cell” can refer to any compartment partially resembling a biological cell in size or form but is synthesized or even entirely composed of non-biological components. The phrase “artificial cell” is also applied to constructions with direct applications, such as drug delivery chambers.
Microencapsulation permits metabolism and the exchange of small molecules within the membrane while preventing the passage of large molecules across it.
The primary benefits of encapsulation include enhanced mimicking within the body, higher solubility of the payload, and reduced immunological reactions. Notably, synthetic cells have demonstrated clinical benefit in hemoperfusion.
About Craig Venter
He is renowned for directing the first draft of the human genome sequence and assembling the first team to transfect a cell with a synthetic chromosome.
In June 2005, Venter co-founded Synthetic Genomics, a company aiming to produce sustainable fuels and biochemicals utilizing engineered microorganisms.
ExxonMobil launched a $600 million partnership with Synthetic Genomics in July 2009 to investigate and create biofuels for the next generation.
Venter continues to work on synthesizing diatomic microalgae tailored for biofuel generation.
Venter is attempting to obtain a patent on the first partially synthetic species, which may be called Mycoplasma laboratorium.
There is conjecture that this line of research could lead to the production of bacteria that have been genetically modified to perform certain reactions, such as creating fuels, making medicines, combating global warming, etc.
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